Interrelation between Heart Failure and Chronic Kidney Disease: A Focus on Molecule Mechanisms
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 585
Special Issue Editors
Interests: chronic kidney disease; hemodialysis; vascular access; cardiorenal syndrome; heart biomarkers; miRNA
Interests: cardiovascular risk in renal patients; vascular function in uremia-biomarkers in renal disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The heart and kidney are interconnected, and this interaction is bidirectional because the acute or chronic dysfunction of the heart or kidneys can induce acute or chronic dysfunction in the other organ.
The term "cardiorenal syndrome" has been applied to these interactions.
Patients with heart failure (HF) have a high risk of reduced glomerular filtration rate, and patients with chronic kidney disease have an increased risk of both atherosclerotic cardiovascular disease, and HF.
Mortality is higher in patients with HF and chronic kidney disease and cardiovascular disease is responsible for up to 50 percent of deaths in patients with renal failure.
Up to 70%–80% of chronic hemodialysis patients display abnormal concentric or eccentric left ventricular hypertrophy (LVH). Cardiac fibrosis due to collagen deposition between the capillaries and cardiomyocytes often overlays LVH, leading to ventricular wall dilatation and diastolic dysfunction: a threatening condition known as “uremic cardiomyopathy”.
The pathogenesis of this interconnection is complex and not yet entirely clear.
Thus, this Special Issue entitled ‘Interrelation Between Heart Failure and Chronic Kidney Disease: A Focus on Molecule Mechanisms’ discusses recent advances in molecular mechanisms involved in the interconnection between the heart and kidney. Topics related to both original and reviewed articles are welcome.
Dr. Pierangela Presta
Dr. Coppolino Giuseppe
Guest Editors
Manuscript Submission Information
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Keywords
- cardiorenal syndrome
- heart failure
- chronic kidney disease
- uremia
- left ventricular hypertrophy
- biomarkers
