Advancing Vaccine Delivery: Improvements to Enhance Trust and Uptake

Dear Colleagues,

Vaccines have been a remarkable success, significantly reducing the incidence of morbidity and mortality worldwide. However, their current delivery technologies must be improved to develop vaccines against infectious diseases that have been difficult to control with conventional approaches. These improvements should consider using novel adjuvants or alternative delivery methods, such as mucosal immunization. Mucosal delivery is crucial for protecting against pathogens that infect mucosal sites, e.g., sexually transmitted diseases.  Alternative delivery approaches like mucosal administration could also improve compliance with existing vaccines. One example is needle-free delivery devices for safer mass-immunization campaigns. In addition, Innovative approaches to vaccine delivery that include sustainable financing can promote vaccine confidence and uptake. For example, involving community leaders and health workers in vaccine delivery, using social media and trusted communication channels to spread awareness, and integrating vaccination and other services, can enhance vaccine trust and uptake. This Special Issue welcomes original research, reviews, and viewpoints that identify lessons and learnings on effective and innovative ways of delivering vaccines, improving vaccine confidence and uptake.

Dr. Wenhui Mao
Guest Editor

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• trust
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• vaccine uptake
• routine immunization