Sorting of Circulating Tumor Cells/Extracellular Vesicles Using Microfluidics
A special issue of Micromachines (ISSN 2072-666X).
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 369
Special Issue Editors
Interests: microfluidics and BioMEMS; circulating tumor cell isolation; magnetic-based cell sorting; magnetic-based nanoparticle sorting; simulation and fabrication of microfluidic-based biomedical devices; exosomes
Interests: biosensors; electroanalytical; diagnostics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Precision medicine has been a popular subject featuring personalized therapy development. Unlike traditional therapies which may rely on a one-drug-fits-all model, more newly developed technologies such as molecular diagnostics, systems biology, are applied in precision medicine to classify individuals into subpopulations so that more specific treatments can be implemented. An important application of precision medicine is in cancer treatment. The development of methods for the non-invasive detection of biomarkers could lead to new screening tests for early diagnosis of cancers. However, the detection and isolation of biomarkers such as circulating tumor cells (CTCs), extracellular vesicles, are technically challenging. Microfluidics is widely studied as a next-generation technology for new biomarker sorting, analysis, and clinical application in cancer treatment, for the fact that it provides methods for the handling of biological samples at micro/nano scale with high precision. As such, microfluidic technologies like CTC isolation chips have been proved to be important supplements for cancer diagnosis, prognosis, and therapeutics. Accordingly, this Special Issue seeks to show case research papers and review articles that focus on: (1) novel designs, fabrication, control, and modeling of microfluidic devices for circulating tumor cell sorting, isolation, detection and analysis; and (2) new developments of microfluidic technologies for extracellular vesicle sorting and clinical application.
Dr. Kangfu Chen
Prof. Dr. Valber de Albuquerque Pedrosa
Guest Editors
Manuscript Submission Information
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Keywords
- Microfluidics
- circulating tumor cells
- extracellular vesicles
- fabrication
- modeling
- clinical application
