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Circadian Rhythms in the Molecular Pathogenesis of Chronic Diseases: Implications for Prevention and Therapeutic Strategies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 24

Special Issue Editors


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Guest Editor
Division of Endocrinology and Metabolism, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15203, USA
Interests: circadian rhythms; cell-intrinsic clocks; molecular underpinnings; cardiometabolic diseases; chronotherapy interventions
Department of Diabetes Complications & Metabolism, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA
Interests: circadian clock regulation of metabolism; circadian clock-controlled epigenetic mechanisms; adipose tissue growth and metabolic capacity; skeletal muscle development; growth and remodeling

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Guest Editor
Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA
Interests: toxicity of cholesterol in foam cells; atherosclerosis; cardiovascular disease

Special Issue Information

Dear Colleagues,

Circadian rhythms exert pervasive temporal control on diverse physiological processes to maintain homeostasis. Disruption of the daily rhythmic oscillations, driven by the cell-intrinsic clocks, is increasingly prevalent in modern lifestyles due to widespread factors such as shift work, artificial lighting, and social jet lag. Circadian disruption significantly impairs biological functions and predisposes individuals to the development of a myriad of chronic conditions, including cardiometabolic disorders. Molecular insights into the pathogenesis of chronic diseases linked with circadian misalignment raise the possibility of developing targeted interventions to counteract these effects. This Special Issue will address "Circadian Rhythms in the Molecular Pathogenesis of Chronic Diseases: Implications for Prevention and Therapeutic Strategies". The current collection of articles, through expert insights and new research findings, aims to interrogate clock-controlled molecular underpinnings linking circadian rhythm and the development of chronic diseases. Emphasis is placed on molecular studies that drive chronotherapy interventions and clock-targeting preventive or therapeutic measures that may alleviate the multi-morbidities due to circadian disruption.

Dr. Vijay K. Yechoor
Dr. Ke Ma
Dr. Antoni Paul
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • circadian rhythms
  • cell-intrinsic clocks
  • molecular underpinnings
  • cardiometabolic diseases
  • chronotherapy interventions

Published Papers

This special issue is now open for submission.
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