Enhancing Cancer Treatments through Fluorescence-Guided Surgery

Dear Colleagues,

Fluorescent-guided surgery (FGS) is a promising strategy, applied by surgeons for complete cancer resections with reduced damage to surrounding healthy tissue. FGS involves the use of photosensitive agents, aiding surgeons with real-time intraoperative fluorescent visualisations of cancers. It is successfully applied to delineate between cancerous and healthy tissues. FGS reduces tumour burden more efficiently and reduces the rate of tumour recurrences. In recent years, there has been an ongoing effort to develop the next generation of photosensitive agents that aim to address the limitations of current clinically used photosensitive agents. These studies have sought to exploit tumour physiologies and biomarkers, through cancer-targeting nanotechnologies, improving the uptake of agents; with deep NIR agents improving visual performance and the increase in FGS-specific sensitivity and specificity.

I am pleased to invite you to submit a manuscript relating to your interests in FGS. I welcome primary research articles, literature reviews and timely short communications that can impact the current state of FGS research. In particular, we welcome manuscripts focusing on the development of new fluorescent agents, payload delivery platforms, multimodal agents that fluoresce and exert tumour toxicity and any exciting advances in clinical applications.

I look forward to receiving your contributions.

Dr. Ibrahim Khot
Dr. Yazan Sulaiman Khaled
Guest Editors

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• fluorescence-guided resection
• fluorescent imaging
• cancer surgery
• tumour targeting
• intraoperative staging
• oncological fluorescence
• precision medicine